Graeme Howe
Assistant Professor
Biological & Organic
Department of Chemistry
People Directory Affiliation Category
Chernoff Hall, CHE512 (office), CHE438N (lab)
Department of Chemistry
90 Bader Lane
Queen's University
Kingston, Ontario K7L 3N6
Lab Tel: 613-533-2690
Research Interests
Origins of enzymatic catalysis
Elucidation of enzyme mechanisms
Understanding natural and directed evolution of enzymes
Evaluating the role of protein dynamics in catalysis
Organic reaction mechanisms
Kinetic isotope effects as mechanistic probes
Computational modelling of transition states
Interplay of solvent effects and transition state structures