Photo: Graeme Howe

Graeme Howe

Assistant Professor

Biological & Organic

Department of Chemistry

People Directory Affiliation Category

Chernoff Hall, CHE512 (office), CHE438N (lab)
Department of Chemistry
90 Bader Lane
Queen's University
Kingston, Ontario K7L 3N6
Lab Tel: 613-533-2690
 

Research Interests

Origins of enzymatic catalysis

Elucidation of enzyme mechanisms 

Understanding natural and directed evolution of enzymes

Evaluating the role of protein dynamics in catalysis
 

Organic reaction mechanisms

Kinetic isotope effects as mechanistic probes

Computational modelling of transition states

Interplay of solvent effects and transition state structures