The Department of Chemistry and the Department of Biomedical and Molecular Sciences collaborative study was published in the Journal of the American Chemical Society.
The collaborative work of Allingham, Craig & Evans labs was published in the Journal of the American Chemical Society. This publication demonstrates the ability to produce a truncated synthetic derivative of the actin-targeting marine toxin mycalolide B impairs ovarian cancer cell motility and invasion of extracellular matrix. This is an important and exciting step toward developing a new class of cancer therapeutics that can inhibit cancer metastasis. Cancer metathesis accounts for approximately 90 percent of the annual deaths, and this approach is an important step in dealing with this dreadful disease.