Department of Chemistry



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Introducing Dr. Graeme Howe to the Department of Chemistry

Photo: Dr. Graeme HoweEnzymes are remarkable catalysts that can accelerate reactions by as much as 1026-fold over the corresponding spontaneous processes. Despite intense scrutiny, the origins of this catalysis remain unclear. Dr. Graeme Howe’s research is focused on the use of physical organic chemistry to understand how enzymes achieve these accelerations. By studying enzymes along their evolutionary trajectories, the Howe group aims to understand both how modern enzymes function and the mechanisms by which evolution produces these modern catalysts.