Organic & Biological Radical

Chemistry @ Queen’s

What’s New?

Join the Group!

Di Hu has successfully defended her thesis. Congratulations Di!

 

Susheel’s paper “Tyrosine Analogs for Probing PCET Processes in Peptides and Proteins” is published in JACS!

 

Luca, Di and Jay’s paper “Unexpected Acid-Catalysis in the Reaction of Peroxyl Radicals with Phenols” is published in Angewandte Chemie!

 

Tag and Susheel’s paper “Pyridine  and Pyrimidine Analogs of Acetaminophen…” has been selected  a “hot paper” by the editors of Organic and Biomolecular Chemistry!

 

 

 

Copyright 2010, The Pratt Group. Correspondence should be directed to Dr. Derek Pratt, Department of Chemistry, Queen’s University

90 Bader Lane, Kingston, Ontario, Canada K7L 3N6.  Tel: 1-613-533-3287 Fax: 1-613-533-6669 Email: derek.pratt@chem.queensu.ca

The Pratt Group

The reactions of free radicals has long captured the attention of organic chemists. Radicals are used to make the bulk of the world’s polymers, are responsible for the deterioration of essentially all petroleum-derived products, from polymers to lubricating oils, and are even used to carry out complex synthetic transformations. The intervention of radical intermediates in biological contexts also attracts widespread interest due to their role in aging, the development of degenerative diseases, and the processes that drive life: respiration and photosynthesis. In our lab, we make use of synthetic organic chemistry coupled with the concepts and tools of physical organic chemistry and even molecular biology to address questions involving radicals in organic and biological chemistry. We currently have four particular foci:

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